Tokyo Butei High School is a special school where armed detectives—"Butei"—are trained to use weapons. Kinji Tōyama is a second year student who has a special ability, but he keeps it a secret to maintain an ordinary, peaceful life. However, when he gets caught in a bombing on the way to school, he encounters Aria H. Kanzaki, the most powerful S-Rank Butei student in Assault Studies.
Ganta Igarashi has been convicted of a crime that he hasn't committed, and sent to a new, privately owned and operated prison, where the inmates are the main attraction in a modern day twist to the gladiatorial coliseums of ancient times. Throw in a healthy dose of weird little girl, some new-found super powers, and a little conspiracy theory, and you have Deadman Wonderland.
Takato Matsuda, Ruki Matsuno, and Lee Jenrya are children who have, by fate, recieved real Digimon, unlike the imaginary ones in the card game they play. Each of the children, or "Digimon Tamers", have their different views on how Digimon should be treated. But when other Digimon begin to appear around Japan, they must put aside their differences to fend off the digital intruders; even though Yamaki, who is the head of a secret organization called Hypnos is trying to eliminate all of the Digimon himself.
The Diclonius, a mutated homo sapien that is said to be selected by God and will eventually become the destruction of mankind, possesses two horns in their heads, and has a "sixth sense" which gives it telekinetic abilities. Due to this dangerous power, they have been captured and isolated in laboratories by the government. Lucy, a young and psychotic Diclonius, manages to break free of her confines and brutally murder most of the guards in the laboratory, only to get shot in the head as she makes her escape. She survives and manages to drift along to a beach, where two teenagers named Kouta and Yuka discovers her. Having lost her memories, she was named after the only thing that she can now say, "Nyuu," and the two allow her to stay at Kouta's home. However, it appears that the evil "Lucy" is not dead just yet...
Lain Iwakura appears to be an ordinary girl, with almost no experience with computers. Yet the sudden suicide of a schoolmate, and a number of strange occurrences, conspire to pull Lain into the world of the Wired, where she gradually learns that nothing is what it seems to be... not even Lain herself.