Futaba is a girl who was in love with a boy named Kō Tanaka in middle school. However, after a misunderstanding, their relationship as friends ends when he transfers schools over summer vacation. In high school, her world is turned around once again when she meets Kō again, this time under the name of Kō Mabuchi.
A dream of falling from the sky...and then birth. Rakka is born from a large cocoon into the Old Home, greeted by a group of females with small wings on their backs and shining halos above their heads. Soon Rakka's own wings grow, a halo is placed on her head and she is told that she must work in the nearby town of Grie. She soon realizes that the town and the entire world they live in are confined behind the Wall, a tall, impenetrable wall that none except the mysterious Toga are allowed to exit.
Lain Iwakura appears to be an ordinary girl, with almost no experience with computers. Yet the sudden suicide of a schoolmate, and a number of strange occurrences, conspire to pull Lain into the world of the Wired, where she gradually learns that nothing is what it seems to be... not even Lain herself.