In 2046, people can access a virtual network known as the Neurolinker via their cellphone terminals. A perpetual victim of bullying, middle school student Haruyuki spends his time absorbed in games in a corner of his local network. One day he is approached by the most famous girl in his school, Kuroyukihime (Black Snow Princess). She gives him a strange program called Brain Burst that has the power to "accelerate the world."
Ken Kaneki is a bookworm college student who meets a girl names Rize at a cafe he frequents. They're the same age and have the same interests, so they quickly become close. Little does Kaneki know that Rize is a ghoul - a kind of monster that lives by hunting and devouring human flesh. When part of her special organ - "the red child" - is transplanted into Kaneki, he becomes a ghoul himself, trapped in a warped world where humans are not the top of the food chain.