Kill la Kill is set at Honnouji Academy, a fictional high school in Tokyo Bay set in Japan that is dominated by its fearsome student council, led by Satsuki Kiryuin. The council members wear special uniforms called Goku Uniforms that grant them superhuman abilities, which they use to oppress the rest of the school's students and staff. Ryuko Matoi, a student wielding half of a scissor-shaped longsword, transfers to Honnouji Academy in search of the owner of the other half of the scissor blade, the person who killed her father. Defeated by the council after interrogating Satsuki over the killer's identity and whereabouts, Ryuko comes across a sentient sailor uniform she names Senketsu, who puts himself on Ryuko. Using Senketsu's special abilities, Ryuko stands up against Satsuki and her henchmen, the Elite Four , to liberate Honnouji Academy from their iron grip and find out the truth behind her father's murder.
Follow the adventures Yuki Yuna and the "Hero Club" she joins as they aim to do their best for the community they live in, ranging from helping other clubs to fighting off mysterious enemies known as "Vertex", all in time to attend classes and have fun.