Eleven years after the introduction of internet-connected, augmented reality eyeglasses and visors, Yoko Okonogi moves with her family to Daikoku City, the technological center of the emerging half-virtual world. Yoko joins her grandmother's "investigation agency" comprised of children equipped with virtual tools and powerful metatags. She quickly crosses paths with Yoko Amasawa, an expert hacker of the virtual environment, as Amasawa relentlessly seeks to "unlock" the mystery of a computer virus that emerges from an inaccessible corrupted space.
The Japanese Ministry of Defense has an anti-paranormal special forces group called the Paranormal Disaster Countermeasure Headquarters. They're the ones responsible to protect Japanese soil and its people from supernatural and paranormal events. However, things didn't go so well in one of their missions, which leads to intervention by the Ministry of Enviroment's Supernatural Disaster Countermeasures Division after the PDCH has sustained large numbers of casualties battling demons.
The story follows Issei Hyōdō, a dim-witted, lecherous second-year high school student who is killed by a girl on his first date ever. Issei is reincarnated as a devil, and from that day forward, he serves as an underling of Riasu, a high-level devil who is also the prettiest girl on Issei's campus.
High school student Homura Suzuko has returned to Ikebukuro, the town where she grew up. But when she gets to school, she finds she has trouble fitting in with the rest of the class. One day, she decides that if she learns to play the card game Wixoss, she might be able to make some friends. She buys a deck set, and when she opens it, the girl on one of the cards begins to move, and speak. "Welcome, Selector." Selectors must battle for control of the five coins that hold all their memories. If they can retake all the coins, they win, and can leave the game. But if they lose, as a penalty--
After experiencing a bizarre dream, Madoka Kaname, a kind 14-year-old girl, encounters a magical creature named Kyube. Madoka and her friend Sayaka Miki are offered the opportunity of gaining magical powers if they agree to make a contract with the strange little being. He will also grant them one wish, but in exchange they shall risk their lives by accepting the responsibility of fighting witches. Invisible to human eyes, witches are catalysts of despair in the areas they inhabit. An ally of Kyube, a magical girl named Mami Tomoe, befriends and encourages the two girls to accept the contract. For an unknown reason, another magical girl named Homura Akemi is determined to prevent Madoka from accepting the deal.
WIXOSS is a card game that's popular with teenagers. Supposedly there exist "LRIG Cards," female character cards with wills of their own. Special girls can hear the voices of the LRIGs, and those who possess them are called "Selectors." These Selectors have card battles in a dimension that other humans cannot access. It's said that whoever triumphs in these battles will have their wish granted. Ruko Kominato is the latest girl to find a LRIG card. She names hers Tama, and without any further explanation is thrown into her life as a Selector.
Yōto Yokodera is a perverted schoolboy who is unable to express his true feelings freely. After hearing about the wish-granting Stony Cat, he decides to try and make an offering to lose his facade, only to meet Tsukiko who wishes instead to be more discreet with her feelings to become more adultlike. Who'd have thought the rumors of the wish-granting Stony Cat turns out to be true; transferring the facade that Yōto wishes to lose into a classmate who needs it more and making it difficult for Tsukiko to show even the slightest of emotions on her face. Being on the same boat, they both search for ways to remedy the situation.
Kazuya Kagami's most treasured possession in the world is the obi left to him by his late mother. The scent of cherry-blossoms infused into it helps him through his day - but he never expected it to save his life, becoming a beautiful kimono-clad girl who calls herself an "artifact spirit." Her name is Kiriha, tsukumogami of the sash, who naturally moves in with him, as he is her "owner." Throw in Chisato, his bespectacled friend, an overprotective older sister who wants to take baths with him, a busty priestess, a seductive sorceress named Kokuyoura, and Kazuya's life has just gotten a lot more interesting.