Professor Utonium and his son Ken have been assigned to study the mysterious Chemical X, which mutates and reacts when buns are dropped into it, becoming Chemical Z. When a strange glacier appears in Tokyo Bay, Ken uses a ray of Chemical Z to break it apart, causing several black rays of light to fall through the city. When the rays strike objects, animals, or people, they turn into monsters. However three white lights also break away and strike three ordinary girls, who gain the power to transform into Powerpuff Z.
The anime re-imagining of the original live-action series follows the Winchester brothers Sam and Dean as they hunt creatures and other supernatural phenomena across the American landscape. The anime will be a 22-episode season that will cover the storyline of the live-action version's first two seasons. The anime project will not only remake the best episodes from the live-action version, but also depict original episodes not seen in the live-action version. Those original episodes will include prologues of the Winchester brothers' childhood, anime-only enemies, and episodes featuring secondary characters from the live-action version.